With the aim of understanding the evolution of chordates, the JGI sequenced the amphioxus genome .... A thorough analysis ... shows that the creature's 19 chromosomes map onto the human genome in 17 segments, each of which is represented four times in the human genome.
"The human genome is a mosaic of these 17 ancestral pieces constructed by two rounds of duplication, followed by gene loss and chromosome rearrangments and fusions. That took some computational gymnastics to sort out, but the evidence is still there," said Rokhsar.
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